3D images of human skin acquired by linefield confocal optical coherence tomography (LC-OCT) acquired at different time points during an optical clearing process by nine different optical clearing agents and control

Updated at: 02/12/2025

This dataset contains three-dimensional images of human skin that allow visualization of the skin structures of the epidermis and papillary dermis at the cellular level.

The dataset contains 10 folders each named according to the optical clearing agent used to induce optical clearing : 9 mixtures and one control as described in the Readme file published also online.

Each folder contains 3 subfolders each corresponding to one of the three volunteers on whom images were acquired using the LC-OCT optical imaging method. Each volunteer is identified (i.e. each subfolder is named) according to the volunteer’s :

  • Sex: F: female or M: male,
  • Age: 31 years for example,
  • Phototype (according to the Fitpatrick’s scale) : 1 for fair-skin, 3 for mid-tanned skin, etc.

Each subfolder contains 10 images in dicom format (i.e. .dcm files) each corresponding to a certain time point during the optical clearing process. The Readme file contains some tips on free software to use to open .dcm files and view them in 3D.

Zaytsev, Sergey; Amouroux, Marine; Tuchin, Valery; Genina, Elina; Blondel, Walter, 2025, "3D images of human skin acquired by linefield confocal optical coherence tomography (LC-OCT) acquired at different time points during an optical clearing process by nine different optical clearing agents and control", https://doi.org/10.57745/PUKO1W, Recherche Data Gouv, V1