European genome-phenome archive (EGA)

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Genomics

Accepted data

Sensitive data from biomedical research. Genetic sequences (generic or specific formats). DNA microarrays: from raw signal files to matrices. Phenotypes (all formats). The repository is recommended for data that is potentially re-identifiable and requires access control. All submissions require the use of an encryption tool (crypt4gh). For other types of genetic data, other repositories should be used. https://ega-archive.org/submission/metadata/submission/FAQ/

Supporting institutions

European Molecular Biology Laboratory European Bioinformatics Institute (EMBL-EBI)

Center for Genomic Regulation

Persistent identifiers

DOI

Volume limit

Data is submitted via a ''submission box'' that cannot exceed 8 TB

Repository provided moderation

Automated and human. Every submission undergoes a documented quality control process (File Quality Control Report). Average time between submission and publication: 1 month.

Viability

Platform launched in 2008. No time limit; storage is described as ''permanent.'' Data is replicated on servers at the Barcelona Supercomputing Center (BSC). The repository is part of the international ELIXIR network.

Notes

The repository recommends the use of controlled vocabularies (Experimental Factor Ontology Database) to describe phenotype data. Metadata schema based on XML, JSON, and that of the ENA repository (https://ega-archive.org/submission/metadata/ega-schema). Embargo: 1 year with the possibility of extension upon justification. Only metadata is made public. Access to the data is subject to a highly regulated authorization request, requiring approval from a committee (Data Access Committee) designated for each dataset.